You are told that at the beginning you might have more gout flares for a few weeks then they will taper off to none. What they do not tell you is Allopurinol can cause a plethora of pretty dangerous side effects other than the intial gout flares.
For the first few weeks I had more flares than I've ever had, which I was prepared for because I was warned. If this medication elimanted gout I could handle a couple rough weeks. What I was not prepared for was constant severe nausea. I felt sick all the time.
Then I started doing some research on Allopurinol, if you are happy with it and don't have any side effects you may want to stop reading.
Dangerous Side Effect 1:
Allopurinol decreases red blood cell platelets which make it easier to get sick and harder to get better. If that wasn't enough it reduces your bloods ability to clot, making you bleed and bruise easier. Not only was I feeling sick from the nausea, I was actually getting sick from a lowered immune system. Here's some info from RxList.com:
"Allopurinol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly." (https://www.rxlist.com/zyloprim-drug/pa ... #important)
Dangerous Side Effect 2:
This is the extremely scary one. According to the company, between 2-6% of patients taking Aloprim or Zyloprim for gout will experience acute liver injury from a hypersensitivity to Allopurinol. Here's the problem. The latency period of a liver hypersensitivity is 2-6 weeks. Thats roughly the same time where your body will be adjusting to the Allopurinol and you are trying to tough it out. This is extremely dangerous because it is often masked by other symptoms. Here's a scary paragraph from the National Library of Medicine: "Allopurinol hepatotoxicity has a high fatality rate, either from acute liver failure or complications of other allergic manifestations such as toxic epidermal necrolysis, vasculitis, pancreatitis and renal dysfunction. African-American race and preexisting renal disease appear to be risk factors for hypersensitivity to allopurinol.
Likelihood score: A (well established cause of clinically apparent liver injury)." (https://livertox.nih.gov/Allopurinol.htm)
DO NOT TRY AND TOUGH IT OUT. This is serious stuff guys. I wanted to share this with you all so you are aware of the risks and dangers, this is the stuff that they won't tell you when the doctor writes the prescription. In my research I believe that 2-6% of patients taking Allopurinol for gout developing liver damage or failure is too low, that statistic is outdated. Hopefully with this information you can make an informed decision on whether or not Allopurinol is right for you.